Champix: The Terror Continues

“I think the drug [Champix Chantix] should be banned because it is crazy. Does anyone know how long this will go on because living alone I don’t know if this will stop before it takes control of me. it has to stop soon I pray”

*Update: If you or a loved one has suffered a bad reaction to Champix and you are based in the U.K., you can report it to the Medicines and Healthcare Products Regulatory Agency (MHRA) here. The more people do that the clearer the true picture will become. Protect others! Report it.*

After four years of collecting smokers’ feedback about Chantix/Champix/varenicline on this site, it is now obvious that no-one is safe from this drug, not even people who have taken it before with hardly any side effects.  This is typical of some of the feedback we are getting from people who have tried a second or third course of the drug because of its high relapse rate:

“I first went on Champix 3 years ago, did the full course and gave up smoking for 2 years.  only side effect was a few weird dreams.  Unfortuneatly I started smoking again so went to get a new course from the doctor.  5 weeks in and I am now close to finishing it all.  I can’t sleep, keep shaking, crying uncontrollably and look at knifes in the draw, pass the bath and see myself lying there with no more problems and it won’t stop.
Doctor stopped me taking them 5 days ago, 2 days later he put me on valium and I’m still not able to control myself without taking valium to put me to sleep.  Currently I’m looking at the valium and thinking if I take the lot then it will stop all this crazy feeling.
worst thing is I know what is causing it but can’t stop.  I think the drug should be banned because it is crazy.  Does anyone know how long this will go on because living alone I don’t know if this will stop before it takes control of me.  it has to stop soon I pray”

No Isolated Case

If you’re reading this and trying to reassure yourself that this is some kind of freak case – it isn’t.  These individual nightmares are going on all over the world, and are seriously under-reported which is why I am screaming about it from the TruthWill Out site and will continue to do so until this evil drug is withdrawn from sale.  Imagine going through this yourself, or someone you love going through that just because they wanted to improve their health and they innocently assumed that the drug had proved safe in clinical trials.

It didn’t: the manufacturer Pfizer hid some of the evidence from a crucial safety review by submitting the reports of hundreds of bad reactions “through the wrong channels” at the Food and Drug administration.  When this fact came to light, the French government withdrew public funding of the drug, citing “safety concerns”.  All the other Health Departments in governments all over the world who have done lucrative deals with Pfizer decided to pretend it didn’t happen, and that is the only reason this terror is continuing.  If you think it’s all about depression and suicide, think again: the list of serious ailments caused by this drug is a long one and many lives have been ruined already.

Champix has aleady caused suicides, murders, violent attacks, horrendous depression, crippling pain, major life-threatening seizures and epilepsy in people who have never had epilepsy before, life-threatening skin conditions where skin blisters up and falls off, damage to optic nerves, increased risk of heart attacks… and as this message proves, it usually doesn’t work in the long run anyway.

If you have taken Champix yourself, and like David the first time round, had hardly any side effects and stopped smoking for a while, you might feel inclined to send me a message saying: “I think Champix is brilliant!”  …not realising you were just lucky the first time round.  David’s advice now would probably be: “Don’t risk it again.”

more smokers’ feedback

 

Champix Chantix 9: Varenicline, murders and suicide

I first heard of Champix (Chantix in the U.S.), otherwise known as varenicline, in May 2007. By July 2008 I had already learned enough about it to arrive at the conclusion that it should never have been passed as if it were safe for use in the UK, Canada or Australia because it was already clear it was causing serious harm in the United States. Before another year had gone by I had made it an express aim of the Truth Will Out Campaign to call for the withdrawal of this extremely unpredictable killer drug. (See Homepage for the original aims of The T.W.O. Campaign.)

*Update: If you or a loved one has suffered a bad reaction to Champix and you are based in the U.K., you can report it to the Medicines and Healthcare Products Regulatory Agency (MHRA) here. The more people do that the clearer the true picture will become. Protect others! Report it.*

Why Champix Should Be Withdrawn Immediately  by Chris Holmes

Finally – and this has taken far too long – the call has begun for Champix to be withdrawn from sale because of the dreadful damage it has done to so many smokers and their families.  Dr Michael Siegel, a Professor in the Department of Community Health Sciences at Boston University School of Public Health has explained why the Black Box Warning on the medication – the strongest type of safety warning there is – is still not sufficient to protect the public.  His voice should not be ignored: Dr Siegel has 25 years experience in the field of tobacco control and has published nearly 70 papers on tobacco.  This is what he says about Pfizer’s dangerous brain-boiling tablet:

http://tobaccoanalysis.blogspot.com/2011/04/rest-of-story-calls-for-removal-of.html

http://tobaccoanalysis.blogspot.com/2011/04/chantix-why-black-box-warning-is-not.html

I’ve Been Saying This For Years Now

I first heard of Champix (Chantix in the U.S.), otherwise known as varenicline, in May 2007.  By July 2008 I had already learned enough about it to arrive at the conclusion that it should never have been passed as if it were safe for use in the UK, Canada or Australia because it was already clear it was causing serious harm in the United States.  Before another year had gone by I had made it an express aim of the Truth Will Out Campaign to call for the withdrawal of this extremely unpredictable killer drug.  (See Homepage for the original aims of The T.W.O. Campaign.)

That was two years ago.  The foot-dragging of medical authorities all over the world with regard to this evil medication has become truly obscene.   Most recently, New Zealand’s medicines approval body Pharmac – which had hesitated over Champix because of serious concerns regarding its safety – finally did a special ‘package deal’ with Pfizer involving the licensing of a number of drugs, including Champix, making it shockingly clear that their former concerns about the safety of New Zealand smokers could be negotiated away if the price was right.  Never mind that the link with suicides was already well established.  Never mind the fact that by this time, it was apparent that the true success rate of the drug (at the one-year follow-up stage) was only about 14%.  The press in New Zealand churned out the familiar marketing hype about the 55% ‘success rate’ once achieved at the 12 week stage in clinical trials, and a Pfizer spokesperson added the  platitude that the “benefits outweighed the risks”.  What they really meant was, the benefits to THEM outweighed any risks to smokers lives, jobs, health, relationships, liberty etc. as far as THEY were concerned… risks which Pfizer continue to deny can be conclusively linked to the drug anyway.

*Would you like to reply to that denial?  If you or a loved one has suffered a bad reaction to Champix and you are based in the U.K., you can report it to the Medicines and Healthcare Products Regulatory Agency (MHRA) here. The more people do that the clearer the true picture will become. Protect others! Report it.  If you live elsewhere, Google “How do I report a bad reaction to a medication in…” (wherever)*

Smokers’ Testimony Doesn’t Count

… as far as Pfizer are concerned, that is.  This is why I encourage all those smokers who have suffered a bad reaction to report it, and make sure their doctor uses the official channels to make that report count.  And although a recent report  found that Champix/Chantix was 18 times more likely to be associated with violent behaviour than any of the other 484 drugs in the study – making it the worst offender of all in terms of aggressive reactions – that is STILL only using the data from the limited number of cases where an official complaint was made against the medication.

Smokers’ testimony counts here, though, on Truth Will Out.  Already we know, from such testimony, that:

– many smokers are STILL not being warned about ANY risks associated with the medication

– many doctors and other medical personnel don’t know much about risks anyway, or dismiss it as ‘media hype’

– many smokers are okay on the drug at first.  THEN it gets nasty

– early results seem much more promising than long-term outcomes actually are

– the last two points have generated massive amounts of PREMATURE praise for the drug

– many sufferers of bad reactions did not know that the drug was to blame

– very bad side effects continue in some people long after coming off the drug.

It seems inevitable that suicidal or violent behaviour in individual cases over the last four years may well have been blamed on the individual rather than the drug.  In court cases or inquests all over the world it seems likely that the connection would probably have been missed, or perhaps dismissed as an attempted excuse.  Certainly the actor Nicolas Williams was thought by some commentators at the time to be using that connection as a way of getting off an assault charge, when he was cleared by a court last June.  But how many have been convicted?

In July last year, Andrew Case  killed his two young daughters and his wife, then hanged himself.  He had been taking Champix, but at the inquest it was stated that none of the drug was found in his blood.  Did the people conducting that inquest fully understand that the horror continues for many Champix victims, sometimes long after the drug is discontinued?  PRETTY IMPORTANT FACT TO BE AWARE OF, DON’T YOU THINK?

A Sure-Fire Way To Get At The Truth About Champix

When people die by their own hand – or as a result of violence, there is always a post-mortem examination.  In this country, and I’m sure in many others, if that person is on any medication from their doctor, a note of this is made as part of the post-mortem and inquest proceedings.  However, if they blew their brains out with a shotgun – or someone else’s brains – then the cause of death is recorded as Death By Shooting.  If they were taking Champix at the time, the cause of death is listed as… Death By Shooting.  This means if Champix really caused that death, Pfizer got away with it.

I suggest that the obvious thing to do is to look back over ALL the violent deaths and suicides which have happened over the last four years, and find out how many of those people were taking Chantix or Champix at the time.  Then compare this information with the same types of cases in the previous four years before that, to see if the Great Global Champix Experiment threw up a spike in the incidence of violent assault, murder and suicide.   Might also be a good idea for anyone accused or convicted of violent behaviour during that time to check for a Champix connection if that was not the way they usually behave.  I’m sure this kind of information could be demanded by anyone under the Freedom of Information Act here in the UK, or obtained by lawyers involved in cases against Pfizer over Chantix/Champix.  Even though this would still be missing the cases where the drug was bought, not prescribed, it would be a very good indicator of the drug’s actual role in all these horror stories and – even if not conclusive in any individual case – enough to get the monstrous concoction banned.

That inevitable event cannot come soon enough.  How many more have to die, Doc?

the book that blew the whistle on the nicotine scam

safer, more effective alternative

 

 

 

This Blog is about Nicotine, Not Champix!

by Chris Holmes

OK it is time to get focussed! When I launched the Truth Will Out Campaign back in March 2008, it was to blow the whistle on the Global Nicotine Scam, not to spend the rest of my working life discussing Champix… or Chantix to give it the alias it goes by in the United States.  Varenicline.  Doesn’t matter what you call it, it still doesn’t work very well unless what you’re after is a mental breakdown and the loss of everything that is dear to you.

That drug is based upon the notion that smokers smoke because of nicotine – an idea which doesn’t stand up to any serious scrutiny, it’s just that no-one was scrutinising it until I published Nicotine: The Drug That Never Was in 2007.

Since then, a study done by Dr Reuven Dar from Tel Aviv University’s Psychology Department (link follows) has confirmed exactly what I was saying in that book: namely that smokers’ cravings are not withdrawal symptoms, and indeed are not related to nicotine levels in any way. Smoking is NOT a drug addiction, it just looks like one if you don’t know the difference between an addiction and a compulsive habit. And doctors currently do not, which is why I wrote the book. To understand the difference, you need to understand how the human Subconscious mind organises and repeats compulsive habitual behaviour. As a hypnotherapist, I’ve spent more than a decade shutting down habits like that with hypnotherapy, usually in one session.

I have done that with thousands of individuals, one at a time. It is not a trick. It is not a parlour game. It is a process of communication and anyone can respond to it if they choose. It is all explained in the book – available as a paperback (£16.95) or a download (£5).  The fact is, both Champix Chantix and Nicotine Replacement Products are all based on a myth in the first place, and that is why they usually fail.  Shame that smokers usually blame themselves for that failure, when they should be blaming those lousy methods!

the book that blew the whistle on the nicotine scam

The Science

more about hypnotherapy
…and then there is this!  We are quite simply right about this.  Sorry, Doc! Sorry, NiQuitin!  The Nicotine Tale turned out to be an embarrassing medical error leading to a collosal global scam.

Can Champix (Chantix) Cause Seizures/Epilepsy?

Tony West the DOJ Assistant Attorney General for the Civil Division was quoted by news releases, “Illegal conduct and fraud by pharmaceutical companies puts the public health at risk, corrupts medical decisions by health care providers, and costs the government billions of dollars”.

by hypnotherapist Chris Holmes

N.B. Please read the comments after this post, as it now transpires that no-one should be prescribed Champix without having a particular gene test FIRST, or it could trigger epilepsy in people with no previous history of epilepsy.

 

*Update: If you or a loved one has suffered a bad reaction to Champix and you are based in the U.K., you can report it to the Medicines and Healthcare Products Regulatory Agency (MHRA) here. The more people do that the clearer the true picture will become. Protect others! Report it.*

Check this out Widow Sues Pfizer

There is a link in that story to the actual lawsuit, and in that there is mention of evidence that Chantix not only triggers suicides, but many other nasty side effects including seizures. Recently I was contacted by a very distressed person who started having severe epileptic fits only two months after starting on the drug, and it has ruined that person’s life.

If anyone else has had seizures or developed epilepsy after taking this drug – or knows of anyone who has – with no previous history of either condition before taking it, please let us know.

The manufacturers of Champix/Chantix, Pfizer, have an impressive criminal record according to this article by Neil Byrne from 2009:

This week Pfizer settled with the Department of Justice for $2.3 billion, the largest health care fraud settlement in the history of the DOJ. It resolved their criminal and civil liability arising from the illegal promotion of certain pharmaceutical products. Pfizer “off labeled” drugs for uses the FDA didn’t previously approve of. $1 billion was allocated to resolve allegations under the civil False Claims Act that Pfizer illegally promoted the drugs Bextra, Geodon an anti-psychotic drug, Zyvox, an antibiotic, and Lyrica, an anti-epileptic drug. What is worse is that Pfizer is a habitual criminal company since they have been found guilty before in a similar case.

Tony West the DOJ Assistant Attorney General for the Civil Division was quoted by news releases, “Illegal conduct and fraud by pharmaceutical companies puts the public health at risk, corrupts medical decisions by health care providers, and costs the government billions of dollars”. Perhaps this massive fine will curtail Pfizer to some degree, but they will likely need at least three strikes. We think this is the beginning of more and more lawsuits against pharmaceutical companies for cross labeling, inadequate tests and warnings, and drugs that create suicidal thoughts, and aggressive behavior. Consumers need to fully perform their due diligence before taking drugs which have clear controversial effects. Chantix and Zyban have a new warning that the drug can produce suicidal thoughts and behavior. Do you want to stop smoking or stop life?

Full article here.

If you live in the U.S. and are connected to a Chantix suicide case, this may be helpful to you.

If you just want to stop smoking safely and easily, more info here.

*Update, 27.02.12.  In EVERY SMOKER a gene test is required before Champix can be prescribed to make sure you do not have any genetic mutations that would make Champix trigger seizures.  Failure to do this in each and every smokers is “playing poker with peoples’ lives”.

Samantha Dearnaley has sent in this rather technical update from her own research… note the P.S. at the end:

Hi Chris,
just thought I would send you this:  Mutations in either a4 or b2 subunits can cause autosomal nocturnal epilepsy. There is evidence that
ADNFLE can be due to dysfunction of neuronal nicotinic acetylcholine receptors (nAchR). The responsible mutation was subsequently identified as a missense mutation which replaces a serine into phenylalanine (ser248phe) in the a4 subunit gene (CHRNA4) of the neuronal nAchR. This mutation affects the second transmembrane domain (M2) which has been shown to form the wall of the ion channel. This has been the first, and to date only, mutation described in an idiopathic epilepsy. Mutations in mitochondrial DNA, cystatin B and defects causing abnormal neuronal storage, all resulting in neuronal destruction.
Varenicline an a4b2 nicotinic acetylcholine receptor partial agonist, as you can see it works by binding to the same receptors a4b2. I have got this info from Oxford journals, Human molecular genetics.
Kind Regards
Samantha Dearnaley.
PS. I have had another person got in touch yesterday with similar thing, again after Champix. People who want to take this drug should have a gene test done, to see if they have any mutations before they take it, to stop this happening to other people. Its like playing poker with peoples lives. Would this drug still end up costing the NHS less that NRT if they had to do a gene test on everyone?  I don’t think so.
[Chris says:  Not sure it costs less than NRT anyway, though that may have been the hype.  Latest research from Harvard proves NRT doesn’t work at all in the long run – no better than willpower, anyway – didn’t someone say that years ago, though?  Oh yes, it was ME!  Thanks Harvard!  But they’re still prescribing it, aren’t they?  “Evidence-Based-Medicine”, folks!  Evidence is all that’s required to make it bona fide – any evidence will do – even hard evidence that it doesn’t work at all!]

 

86% Failure Rate for Champix

“In a multicenter, randomized, double-blind phase II clinical trial, 638 men and women aged 18-65 who smoked an average of 10 cigarettes per day during the previous year, without a period of abstinence of more than 3 months, where put on placebo, bupropion (another drug used as a smoking cessation aid, brand name Zyban®), or different treatment schedules of varenicline for 7 weeks. Subjects were tested for continuous quitting by measuring exhaled carbon monoxide. After one year, the success rates were 14.4%, 6.3% and 4.9% for varenicline, bupropion and placebo, respectively.”

That was from WikiNews, August 15 2006. Link to this article at the end of this post.

This is interesting because it demonstrates what we can expect in long-term results from new medications (boosted by hype and fresh expectations) compared to old ones which no longer are. Elsewhere on this site I have quoted results for willpower alone from various studies giving us figures of anywhere between 4% to 8% when the results are reviewed at one year. So the placebo (dummy medication) figure given above, 4.9%, is entirely consistent with that. But look how Zyban (bupropion) had also fallen within the normal placebo or willpower range by 2006, whereas earlier reports had suggested it had long-term outcomes of around 13% to 14% – same as the new varenicline (champix, chantix) scores here. So will Champix too fall back within the expected range for willpower or dummy pills once all the hype has passed?

It seems likely. We have certainly seen that with Nicotine Replacement products which were credited with 10% to 20% success rates when the University of Iowa study was carried out in 1992, but we now know from several different independent studies that the current outcomes at one year are a miserable 5% to 6%, once again well within the willpower range.

So this indicates that even in 2006, the long-term outcomes of this so-called “new wonder drug” were no better than the previous “wonder drug” Zyban, which is no longer even managing a miserable 14% success rate now that it isn’t regarded by anyone as a wonder drug any more. Clearly, the difference is entirely accounted for by suggestion and heightened expectation.

That’s not science. That’s marketing. And a complete waste of precious NHS resources.

WikiNews August 15 2006

Hypnotherapy works best, according to the study by the University of Iowa. Find out more in the Evidence section of this site, and here.

Meanwhile, the reports of bad reactions are piling up just as I predicted last year (link).